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1 definition by Kincaid Kjeedo

 
1.
"mano y mano" is Spanish for Hand to hand. Usually associated in engaging in throwing fisticuffs with two or more people, usually two.

Is layman's terms, a fight, but not usually followed closely to it's meaning. Often times, swords, or other weapons, not involved with guns or firearms, are associated with the term.
All right, Robin. Let's go at it. a fight to the death, you and me, Mano y mano, just you and me and my GUARDS!
ayon kay Kincaid Kjeedo ika-09 ng Hunyo, 2006