Top Definition
A highly toxic substance with origins in Australia. Immunity from the deadly properties of iocane can be built up over a period of time if it is introduced in minute portions.

As read/seen in "The Princess Bride": the name was most likely derived from a slightly altered anagram for cocaine, a commonly used drug during the time the book/movie were written (1973, 1987 respectively)
Buttercup: "And to think, all that time it was your cup that was poisoned!"
Man in black/ Westley : "They were both poisoned. I've spent the last few years of my life building up an immunity to iocane powder."
#the princess bride #iocane #westley #william goldman #rob reiner #vizzini #carey elwes #buttercup #inconceivable #princess #bride
ayon kay Whompy Geeb ika-31 ng Agosto, 2011
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