the pairing between Isida Uryuu and Inoue Orihime from the anime/manga Bleach. the word derives from combining Ishi (Ishida) and Hime (Orihime) together. It is very popular among Ichiruki fans.
ZOMG! The Soul Society arc had so many examples of IshiHime moments!
ayon kay Sushi615 ika-06 ng Abril, 2008