Top Definition
Your sister who looks after you and loves you unconditionally. Can be used to describe a great friend as well, but primarily used to describle your female sibling.
1) Mark, this is my big Shishie. Shishie, this is Mark.
2) Lub you, my Shishie
#sister #best friend #soul sister #sheshe #sissie
ayon kay Shishie ika-19 ng Marso, 2008
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