Used as a verb in a threatening tone, can be used to mean "fuck up," "kill," etc...
You fuckin' touch me again and I'll differentiate ya!
ayon kay Jason McAaron ika-14 ng Mayo, 2008
to distinguish from similar options
What differentiated this start-up portal was a relationship with urbandictionary.com
ayon kay Alexander Zubatov ika-17 ng Marso, 2007