Top Definition
When you are really pissed off at someone who is normal(not retarded in anyway) and has a slightly down syndrome look face, you yell at them "what the fuck are you looking at, you down syndrome motherfucker!! This releases stress and puts a great big smile on your face. Try it today!
No examples needed for down syndrome motherfucker. You can fit it in with just about anything.
ayon kay Mr. Fuko ika-18 ng Pebrero, 2011

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