Top Definition
to give in to one's sexual urges in a quick manner; usually referring to females
dang i was with abby for 10 mintes when she was ready to give it up!
ayon kay the give it upper ika-02 ng Marso, 2004
to cheer for someone, or what they bring to the game
Give it up to your dj on the 1-2s keepin it crunk for the party
ayon kay DJ Kayla ika-29 ng Pebrero, 2004
A request for praise which can be issued either by the recieving party or a third party.
Give it up for my man DJ Mike!
ayon kay Majik Fox ika-28 ng Pebrero, 2004
Have sex
Man, she finally gave it up last night
ayon kay Lucky Charms ika-29 ng Pebrero, 2004
To cease efforts now otherwise pointless
"Just give it up man, she's not interested in you."

"You'd better give it up, unless you're rollin' for a bitch-slap."
ayon kay Krispy ika-29 ng Pebrero, 2004
give sex to
You're not getting your money till you give it up.
ayon kay Anonymous ika-16 ng Hunyo, 2002
to give in to temptation
"Yo mane, that hizzo is expecting some chedda if she be givin it up
ayon kay MC Rizzle ika-03 ng Marso, 2004

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