A hickey or love-bite. Named after the biblical mark placed on Cain after he killed his brother... 'cause when you've got it, everyone knows what went down last night.
"Dude, did Jack screw that chick he was with last night?"
"I dunno, but you saw the Mark of Cain he's been flaunting."

"Hey, I'm digging the Mark of Cain."
"Yeah. I think my gf's a vampire, actually."
ayon kay Actaeus ika-01 ng Nobyembre, 2009
Top Definition
1. Another word for niggers. He killed his brother Abel and was banished. Nature would no longer support him. The blackness of the nigger is the mark of cain.
My grandfather never let niggers into his house for no matter what and he stated they carry the mark of cain and should be banished to their ghetto..
ayon kay shdwsclan ika-22 ng Mayo, 2009
(Using Supernatural logic here)
When Cain and Abel were born, Lucifer had already planned on taking Abel. After they made their sacrifices to God, Lucifer appeared to Cain. He told him how he planned to take his brother, but Cain would not let him. Lucifer said if Cain killed Abel, Abel would go to heaven. But, Cain would be stuck on Earth with a mark (later known as the Mark of Cain). He could never age, and he could never love. He soon became a monster, killing for the joy of the kill.
Cain warned Dean of the trouble the Mark of Cain would bring, but Dean took it on anyway. He accepted the heavy burden in order to kill the knight of hell known as Abadon.
ayon kay Jesse The Antichrist ika-27 ng Mayo, 2015

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