In mexican spanish it means sleep.

"hacer la meme"

"to do the meme"
estoy muy cansado, voy a hacer la meme.

I'm very tired, I'm going to do the meme.

por favor no hagas la meme con mi esposa.

please don't do the meme with my wife.
ayon kay delriego ika-01 ng Mayo, 2009
A long stading traditional name for a grandmother. Perhaps of French origins. Usually a rather upbeat young at heart grandparent who knows that the traditional grandparent endearments do not quite fit them!
My MeMe is teaching me to ski!
ayon kay MeME F ika-04 ng Pebrero, 2010
In essence of, pertaining to, or the being of Kanye West.
"Hey, remember that one song by that meme-fuck Kanye West?".... "No, no I do not."
ayon kay meowmilkmonkeyman ika-16 ng Setyembre, 2009
A pervasive idea within a given culture. The idea may be spread through all channels of communication (word of mouth, photography, ad campaigns, television, &c.). The goal of the meme is to change the thought patterns of the populace.
-CNN's take on the war and how it's a good, just war.
-popular tv jingles
ayon kay zZah ika-26 ng Nobyembre, 2003
A Vagina
wow that bitch just kicked me in the Meme
ayon kay nonserviun ika-22 ng Pebrero, 2010
Another word for grandmother. Loves contry music and yodeling. Wears big owl glasses and has a dry sense of humour. But when she laughs, SHE LAUGHS!
'Wow, meme is wearing her owl glasses again'

-turns on yodeling- Wow, what a meme
ayon kay BritneyBreakout ika-30 ng Enero, 2009
Sister, or someone who is just like a sister.

Pronounced "may may".

The generally accepted spelling is Mei Mei from the Chinese word for little sister.

Origin: The sisters shout it at each other at the end of JOY LUCK CLUB.
Meme!!!!!

My brother just got married, so now I have a new meme :).
ayon kay Meme1 ika-23 ng Abril, 2009

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