When you have uncontrolable bowels...aka Diarrhea.
I went to Pancho's Mexican Buffet, and before I could get to the table, I have an onset of the mudbutts... I seriously shit my pants.
ayon kay SnakeFight! ika-22 ng Abril, 2006
An uncontrollable bad case of diarrhea that feels as if mud is oozing out of your ass.
After drinking a case of beer and eating some bad Mexican food, I got a severe case of mud butt.
ayon kay toast455 ika-05 ng Hulyo, 2005
a severe case of diarrhea.
My friend Kris ate bad sushi last night and today he has mud butt.
ayon kay EVCESQ ika-26 ng Enero, 2007
horrible runny shyt; anal leakage
::WARNING::
Eating WOW potato chips may cause mud butt.
ayon kay Bongwater ika-15 ng Abril, 2004
Mud butt is just another term for "Diarrea".
You chugged a bottle of soy sauce?

-Yeah.
Your going to have a serious case of mud butt, very soon.
ayon kay Nicsta ika-31 ng Hulyo, 2009
Similar to explosive diarea but more intense and can cause more pain in the anus
I got mudbutt from that roastbeef sandwich!
ayon kay tiweryopo ika-11 ng Pebrero, 2008
(muhdh - buht) n. med. (usu. pre. by 'the') Mud Butt is a common affliction of the anus and the glutteal crevice, affecting mainly (but not limited to) "heavies". The condition usually occurs 30 to 45 minutes after defecation, especially if sufferer engages in physical activity within this time. Sweat and some remaining feces (though one's wiping habits may be immactulate) mix in the glutteal crevice, causing mild discomfort and, if not treated, a raw ass.
See how Rico is walking funny? He took a dum about 30 minutes ago. I bet he's got the mud butt.
ayon kay Pork King ika-04 ng Nobyembre, 2005

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