A puny, weak, frail person; someone who can easily be defeated. This kind of peron should not pick fights with a larger, stronger person.
Little guy: You're an asshole! Let's take this outside!

Big guy: Don't fuck with me or I'll break you in half, you fucking pipsqueak!
ayon kay Laura ika-18 ng Marso, 2005
An Unimportant, insignificant person.
"SB9Dragon is a Pipsqueak"
ayon kay hanek ika-13 ng Agosto, 2004
a small jerk that does everything to be annoying
You little pip squeak why do u have to be so annoying?!
ayon kay Danville EMT ika-05 ng Abril, 2007
A small person. A child or animal that is cute.
The pipsqueak is crying again.
ayon kay Morikahjo ika-13 ng Agosto, 2009

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