Top Definition
A slang phrase referring to nausea of such extreme intensity that the physical act of vomiting "feels" comparable to expelling the contents of your viscera or gray matter (brain).
If you drink too much alcohol, you'll be "puking your brains out" in front of everyone.
ayon kay David in California ika-23 ng Oktubre, 2006
5 Words related to puking your brains out

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