To have sex with a dog.
Jize Layo screwed the pooch for his new film, "Jize Layo does a dachsund IV"
ayon kay Jose Loya ika-14 ng Agosto, 2005

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Past tense of making a major mistake
"Man, I really screwed the pooch when I talked to my boss while I was druck last night."
ayon kay Quentin ika-31 ng Hulyo, 2003

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Another way of saying "blew it" or "messed up".
"You really screwed the pooch on that one dude".
ayon kay Barb ika-09 ng Setyembre, 2004

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The act of really messing things up.
Damn, i really screwed the pooch on that one.
ayon kay madmanmarx ika-10 ng Oktubre, 2007

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A way in which to describe a mistake or blunder.
"That computer's a lemon, I really screwed the pooch on that deal!"
ayon kay c. Wallace ika-21 ng Mayo, 2004

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To commit a blatant heinously humiliating error.
When he got drunk and took on the ninja, he really screwed the pooch.
ayon kay postmachoguy ika-03 ng Enero, 2009

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to screw up
Boy who ever approved the new Big Tex design really screwed the pooch!
ayon kay screwedthepooch ika-04 ng Oktubre, 2013

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Screwing the pooch is a nonsensical action that is being done while a major fuck up is occuring or has occured.
Management have screwed the pooch while the competition gained the upperhand.
ayon kay ANTZILLA ika-13 ng Hulyo, 2014

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