Similiar to a "freek a leek", this kind of women also engages in sexual acts for fun, however, is driven into a deviant frenzy fueled by the drug "meth" and hence the "tweek" is incorporated.
"Damn yo, we was out in Riverside partying with some of my cousin's homies, next thing you know these dudes start racking glass and these straight up tweek-a-leeks was all up on me.."
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